Treatment Research Collaboration

RESEARCH STUDIES

The Treatment Research Collaboration is currently undertaking pioneering research into PTSD and other complex military-related mental health issues.

We aim to test innovative psychological, social, and neurobiological treatments and delivery methods. This will include a particular focus on early intervention to reduce the cumulative impact of PTSD and related disorders.

FEATURED STUDIES

Attention training to augment veterans’ PTSD treatment (the ACTIVATE trial)

In this randomised-controlled pilot trial we want to find out if undertaking an innovative cognitive intervention, known as Attention Training, improves the outcomes of veterans undertaking standard treatment for PTSD.

This pilot is taking place in Brisbane in collaboration with Toowong Private Hospital and Tel Aviv University.

The UNPAC study

In this study we want to understand how everyday thoughts, feelings, and actions might influence problem anger. Using innovative research methods, we’ll use modern smartphone technology to investigate what daily factors contribute to experiences of anger in Australian veterans.

This study will be recruiting Australia wide, and is open to Australian veterans with access to a smartphone.

Treatment augmentation for PTSD: A systematic review

In this review we systematically mapped the ways researchers are currently augmenting evidence-based PTSD treatments. This involved reviewing all randomised controlled trials (RCTs) which included an intervention designed to augment a first line PTSD treatment. The findings revealed a wide variety of approaches to augmentation. Most of these approaches were largely ineffective, with the exception being those which targeted general cognitive enhancement strategies. However, as many of the augmentation approaches were evaluated in one RCT only, much more empirical research is needed to fully clarify which are most effectual. For the full copy of the paper, please click on the image above.

Defining response and non-response to treatment in patients with PTSD: A systematic review

In this review we will systematically examine published PTSD treatment trials in order to find out how researchers define treatment response and non-response. This review will highlight the challenges surrounding treatment response and non-response definitions within the area of PTSD treatment. Having clear definitions will help us to work towards a better understanding of when treatments can be considered to be effective.

This review is being conducted at the University of Melbourne.

Does employment affect wellbeing in transitioned ex-serving ADF members? (the EmployWELL study)

In this study we want to investigate how finding meaningful employment influences wellbeing and mental health in transitioning ADF members, in order to help tailor future employment-seeking services. This study is recruiting Australia-wide. If you are interested in participating in this study, please click on the image above.

In Their Own Words Study


The In Their Own Words study explores the PTSD treatment choices of veterans and their expectations and perceptions of treatment. This will help us to understand how treatment can better meet the needs of veterans.

Investigating the comparative efficacy of PTSD treatments: A systematic review and network meta-analysis

This systematic review is examining the effectiveness of Guideline - recommended PTSD interventions in published treatment trials. Through the use of unique statistical methods, this review will determine the relative effectiveness of guideline recommended PTSD treatments, ranking them from most effective to least effective, which can help guide clinicians in decision making surrounding PTSD treatment.

Examining dropout rates from Guideline Recommended PTSD treatment: A systematic review and meta-analysis

This aim of this study is to review and analyse guideline recommended PTSD treatment trials. This study will examine (a) the rates of dropout rates from guideline recommended PTSD treatments, (b) what factors influence rates of dropout, and (c) why patients dropout from treatment. Importantly, the study will investigate whether these factors differ for those with military trauma in comparison to other trauma-exposed populations.
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